发明名称 MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY
摘要 The present invention relates to compounds of formula I, The compounds of formula I are valuable pharmacologically active compounds. They exhibit a strong anti-thrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardio-vascular disorders like thromboembolic diseases or restenoses. They are inhibitors of the blood clotting enzymes, especially factor VIIa and can in general be applied in conditions in which an undesired activity of factor VIIa is present or for the cure or prevention of which an inhibition of factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.
申请公布号 US2010249101(A1) 申请公布日期 2010.09.30
申请号 US20100683736 申请日期 2010.01.07
申请人 SANOFI-AVENTIS 发明人 STEINHAGEN HENNING;SZILLAT HAUKE;FOLLMANN MARKUS;KIRSCH REINHARD;WEHNER VOLKMAR;MATTER HANS;LORENZ MARTIN;NEUENSCHWANDER KENT W.;SCOTESE ANTHONY C.
分类号 A61K31/553;A61K31/167;A61K31/351;A61K31/381;A61K31/4015;A61K31/426;A61K31/4409;A61K31/4465;A61K31/455;A61K31/4965;A61K31/5375;A61P9/00;A61P11/00;A61P29/00;A61P31/12;A61P35/00;C07C237/20;C07D207/12;C07D211/42;C07D211/66;C07D213/90;C07D241/04;C07D241/18;C07D265/30;C07D267/10;C07D277/24;C07D309/08;C07D409/12 主分类号 A61K31/553
代理机构 代理人
主权项
地址
您可能感兴趣的专利