| 摘要 |
PURPOSE: A novel magnetic resonance imaging contrast is provided to prevent allergic reaction and to ensure liver, spleen and lung tissue-specificity. CONSTITUTION: A magnetic resonance imaging contrast contains a chelate compound with phosphate group which is conjugated with paramagnetic material. The chelate compound is phytate, inositol phosphate, or phosphatidyl inositol phosphate. The phytate is a d-myo-inositol-1,2,3,4,5,6-hexakisphosphatel. The paramagnetic material is a transition element. The transition element is Fe^2+, Fe^3+ or Mn^2+. The paramagnetic material is lanthanide element. The paramagnetic material is radioactive isotope. The pH concentration of the chelate compound is 4-9. |
