发明名称 |
4-(-4bromo-2-fluoroanilino) -6-methoxy-7- (1-methyl-piperidin-4-ylmethoxy) quinazoline momohydrate |
摘要 |
The present invention relates to a ZD6474 monohydrate, to processes for the preparation of a ZD6474 monohydrate, to pharmaceutical compositions comprising a ZD6474 monohydrate as the active ingredient, to the use of a ZD6474 monohydrate in the manufacture of medicaments for use in the production of antiangiogenic and/or vascular permeability reducing effects in warm-blooded animals such as humans, and to the use of a ZD6474 monohydrate in methods for the treatment of disease states associated with angiogenesis and/or increased vascular permeability, such as cancer, in warm-blooded animals such as humans. |
申请公布号 |
ZA200802640(B) |
申请公布日期 |
2010.09.29 |
申请号 |
ZA20080002640 |
申请日期 |
2008.03.25 |
申请人 |
ASTRAZENECA AB |
发明人 |
BOOTH, REBECCA JANE;PATEL, ZAKARIYA;MEYRICK, BRIAN ROGER;STOREY, RICHARD ANTHONY |
分类号 |
A61K;A61P;C07D;C07D401/12 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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