METHOD FOR PRODUCING CLONED TRANSGENIC CANIDAE

摘要

The present invention relates to a method for producing a cloned transgenic canine, and more particularly to a method for producing a cloned transgenic canine containing a target gene, the method comprising: enucleating a canine oocyte to prepare an enucleated canine oocyte; transferring a cell transfected with the target gene into the canine enucleated oocyte to generate a nuclear transfer embryo; and transferring the nuclear transfer embryo into a surrogate mother. The present invention demonstrates the possibility of producing large amounts of disease model animals by the successful introduction of a foreign gene and is useful for research purposes in the veterinary science, anthropology and medical science fields.