METHOD OF OPTIMISATION OF HODGKIN'S LYMPHOMA OF IIIA STAGE TREATMENT IN ADULTS

摘要

FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, namely to oncology and can be used for optimisation of Hodgkin's lymphoma of IIIA stage treatment in adults. Method is realised in the following way. In case there are no symptoms of intoxication, patients with histological subtype nodular sclerosis and with histological grade at which 75% and more of cellular nodules contain only dispersed Berezovsky-Stenberg cells located on rich in lymphocytes mixed cellular or fibrohistiocytic background, 2-3 cycles of introductory combined chemical therapy are carried out according to schemes MOPP, MOPPABV or ABVD. After that total or subtotal irradiation of lymphatic nodules is performed. ^ EFFECT: application of invention allows to determine indications for chemical-radiological therapy taking into account versions of histological structure of tumour, ensures long-term recurrence-free survival rate and reduces treatment toxicity. ^ 2 ex