摘要 |
<P>PROBLEM TO BE SOLVED: To provide a dicistronic message using variable intergenic sequences. <P>SOLUTION: The dicistronic message for producing antibodies including an upstream side cistron containing a DNA encoding either heavy chains or light chains of a particular antibody molecule and a down stream cistron containing a DNA encoding either light chains or heavy chains corresponding thereto and having specific antigen binding specificity is provided. In the dicistronic message, the two cistrons are linked by an optimized intergenic sequence. <P>COPYRIGHT: (C)2010,JPO&INPIT |