发明名称 EXPRESSION CONTROL USING VARIABLE INTERGENIC SEQUENCE
摘要 <P>PROBLEM TO BE SOLVED: To provide a dicistronic message using variable intergenic sequences. <P>SOLUTION: The dicistronic message for producing antibodies including an upstream side cistron containing a DNA encoding either heavy chains or light chains of a particular antibody molecule and a down stream cistron containing a DNA encoding either light chains or heavy chains corresponding thereto and having specific antigen binding specificity is provided. In the dicistronic message, the two cistrons are linked by an optimized intergenic sequence. <P>COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2010207241(A) 申请公布日期 2010.09.24
申请号 JP20100116444 申请日期 2010.05.20
申请人 UCB PHARMA SA 发明人 POPPLEWELL ANDREW GEORGE
分类号 C12N15/09;C07K16/00;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/72;C12P21/02;C12P21/08 主分类号 C12N15/09
代理机构 代理人
主权项
地址