发明名称 |
COMPOUNDS |
摘要 |
<p>A compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, wherein R1 is selected from: aryl; heteroaryl; -NHR3; fused aryl-C4-7-heterocycloalkyI; -CONR4R5; -NHCOR6; -C3-7-cycloalkyl; -O-C3-7-cycloalkyl; -NR3R6; and optionally substituted -C1-6 alkyl; wherein said aryl, heteroaryl, fused aryl-C4-7-heterocycloalkyl and C4-7-heterocycloalkyl are each optionally substituted; R2 is selected from hydrogen, aryl, C1-6-alkyl, C2-6-alkenyl, C3-7-cycloalkyl, heteroaryl, C4-7 heterocycloalkyl and halogen, wherein said C1-6-alkyl, C2-6-alkenyl, aryl, heteroaryl and C4-7-heterocycloalkyl are each optionally substituted. Further aspects relate to pharmaceutical compositions, therapeutic uses and process for preparing compounds of formula (I).</p> |
申请公布号 |
WO2010106333(A1) |
申请公布日期 |
2010.09.23 |
申请号 |
WO2010GB00498 |
申请日期 |
2010.03.19 |
申请人 |
MEDICAL RESEARCH COUNCIL TECHNOLOGY;MCIVER, EDWARD, GILES;SMILJANIC, ELA;HARDING, DENISE, JAMILLA;HOUGH, JOANNE |
发明人 |
MCIVER, EDWARD, GILES;SMILJANIC, ELA;HARDING, DENISE, JAMILLA;HOUGH, JOANNE |
分类号 |
C07D471/04;A61K31/437;A61P25/28;A61P35/00 |
主分类号 |
C07D471/04 |
代理机构 |
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