| 发明名称 |
IFNAR2 MUTANTS, THEIR PRODUCTION AND USE |
| 摘要 |
The present invention relates to mutant polypeptides of the beta chain of the type I IFN receptor (IFNAR2 mutant) with enhanced affinity for IFN&bgr; as compared to the wild type protein for prolonging the effect of IFN&bgr; in vivo.
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| 申请公布号 |
US2010239530(A1) |
申请公布日期 |
2010.09.23 |
| 申请号 |
US20100788211 |
申请日期 |
2010.05.26 |
| 申请人 |
YEDA RESEARCH AND DEVELOPMENT CO., LTD. AT WEIZMANN INSTITUTE OF SCIENCE |
发明人 |
SCHREIBER GIDEON |
| 分类号 |
A61K38/21;C12N15/09;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P1/04;A61P1/16;A61P3/10;A61P17/02;A61P19/02;A61P21/04;A61P25/00;A61P31/12;A61P31/14;A61P31/20;A61P35/00;A61P35/02;A61P37/06;A61P43/00;C07K14/715;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02 |
主分类号 |
A61K38/21 |
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