发明名称 Fluorene Compound and Pharmaceutical Use Thereof
摘要 The present invention provides an agent for the prophylactic or treatment of diabetes, diabetic complications, insulin resistance syndrome, metabolic syndrome, hyperglycemia, dyslipidemia, atherosclerosis, cardiac failure, cardiomyopathy, myocardial ischemia, brain ischemia, cerebral apoplexy, pulmonary hypertension, hyperlactacidemia, mitochondrial disease, mitochondrial encephalomyopathy or cancer, namely, a PDHK inhibitor and the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as defined in the specification.
申请公布号 US2010240634(A1) 申请公布日期 2010.09.23
申请号 US20090576605 申请日期 2009.10.09
申请人 JAPAN TOBACCO INC. 发明人 MOTOMURA TAKAHISA;NAGAMORI HIRONOBU;SUZAWA KOICHI;ITO HIROTSUGU;MORITA TORU;KOBAYASHI SATORU;SHINKAI HISASHI
分类号 A61K31/397;A61K31/045;A61K31/415;A61K31/435;A61P3/10;A61P9/04;A61P9/10;A61P9/12;A61P35/00;C07C35/38;C07D231/12;C07D401/12 主分类号 A61K31/397
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