发明名称 |
SCELETIUM EXTRACT AND USES THEREOF |
摘要 |
A composition including as an active ingredient an extract of a plant of the family Mesembryanthemaceae with mesembrenol and mesembrenone as the two major alkaloids present. The invention also relates to the use of the composition as a PDE4 inhibitor and as a serotonin-uptake inhibitor, preferably applied in formulations for the use of the composition as a dual serotonin-uptake inhibitor and PDE4 inhibitor. The invention extends to compositions, such as pharmaceutical compositions or compositions used as dietary supplements, the total alkaloid content of which includes at least 80% (w/w) combined content of mesembrenol and mesembrenone, less than 5%(w/w) mesembrine, and at least 7 % (w/w) mesembranol. |
申请公布号 |
WO2010106495(A1) |
申请公布日期 |
2010.09.23 |
申请号 |
WO2010IB51133 |
申请日期 |
2010.03.16 |
申请人 |
H.L. HALL & SONS LIMITED;GERICKE, NIGEL;HARVEY, ALAN;VILJOEN, ALVARO;HOFMEYR, DEON |
发明人 |
GERICKE, NIGEL;HARVEY, ALAN;VILJOEN, ALVARO;HOFMEYR, DEON |
分类号 |
A61K36/185;A61P11/00;A61P19/00;A61P25/00 |
主分类号 |
A61K36/185 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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