TOPICAL COMPOSITIONS COMPRISING INTERLEUKIN-1 ALPHA AND PEPTIDES AND COSMETIC METHODS THEREOF

摘要

The present invention relates to topical composition comprising interleukin-1 alpha and a hexapeptide of the general formula (I): Tyr-X-Gly-Phe-Leu-Y (I) wherein X is independently GIy, L- or D-AIa; Y is independently Asp or GIu; and a dermatologically acceptable vehicle. Further, the present invention relates to cosmetic methods for the use of the compositions for skin conditioning, reducing cellulite severity, improving skin elasticity and firmness, reducing wrinkles, enhancing collagen and elastin production in skin, reducing stretch marks, reducing and/or preventing scars.