OCT GUIDED TISSUE ABLATION

摘要

The present invention pertains to the field of tissue ablation methodologies, more specifically to ablation methodologies that use OCT ( optical coherence tomograph} ) for real time guidance and feedback Said s} stem pro/ ides an optical coherence tomograph} guided tissue ablation de/ice, comprising a catheter, an optical coherence tomograph} de/ice, a light source operabh coupled to the OCT de/ice, a control unit operabh coupled to a light source, where the OCT de/ice pro/ided on the catheter illuminates for the acquisition of images of target tissues and light actuation of a therapeutic agent situated in the target tissue The OCT guided tissue ablation s} stem ma} also include at least one magnetic field module for generating a localized magnetic field in the target tissue where the localized magnetic field promotes localization of a magnetized therapeutic agent in the target tissue A therapeutic agent localization s} stem is pro/ ided as w ell as a composition for magnetic field-facilitated drug delrvep including a carrier particle which is capable of being manipulated b} the magnetic field and at least one therapeutic agent associated w ith the carrier particle is further disclosed