发明名称 COMPOSICION FARMACEUTICA PARA EL TRATAMIENTO DEL CANCER.
摘要 The invention relates to compositions containing a first compound having TGF-ß1 inhibitory activity and a second compound in the form of an immune-stimulating cytokine, preferably IL-12 or a functionally equivalent variant of same. Said compositions demonstrate synergistic effects on antitumour properties when compared to components acting separately. The invention also relates to compositions containing the aforementioned compounds and to the medical use of same for the treatment of cancer, particularly hepatocellular carcinoma and gastrointestinal tumours.
申请公布号 ES2328330(B1) 申请公布日期 2010.09.22
申请号 ES20080000417 申请日期 2008.02.15
申请人 PROYECTO DE BIOMEDICINA CIMA, S.L. 发明人 RODRIGUEZ MADOZ JUAN ROBERTO;SMERDOU PICAZO CRISTIAN;HERNANDEZ ALCOCEBA RUBEN;ALZUGUREN MAZA PILAR;RUIZ GUILLEN MARTA;LASARTE SAGASTIBELZA JUAN JOSE
分类号 A61K38/18;A61K38/20;A61P35/00;C12N15/00 主分类号 A61K38/18
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