发明名称 |
3, 9-DIAZABICYCLO(3.3.1)NON-3-YL-ARYL METHANONE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS |
摘要 |
This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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申请公布号 |
US2010234384(A1) |
申请公布日期 |
2010.09.16 |
申请号 |
US20070160567 |
申请日期 |
2007.02.13 |
申请人 |
PETERS DAN;TIMMERMANN DANIEL B;OLSEN GUNNAR M;NIELSEN ELSEBET OSTERGAARD |
发明人 |
PETERS DAN;TIMMERMANN DANIEL B.;OLSEN GUNNAR M.;NIELSEN ELSEBET OSTERGAARD |
分类号 |
A61K31/4985;A61P1/00;A61P11/06;A61P15/00;A61P17/02;A61P25/00;A61P25/08;A61P25/28;A61P25/32;A61P25/34;A61P25/36;A61P29/00;C07D471/04 |
主分类号 |
A61K31/4985 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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