发明名称 SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES
摘要 <p>Disclosed are compounds of formula (I) which inhibit the activity of anti-apoptotic BcI -2 or BcI -xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti -aooptotic Bcl-2 protein.</p>
申请公布号 WO2010065865(A3) 申请公布日期 2010.09.16
申请号 WO2009US66790 申请日期 2009.12.04
申请人 ABBOTT LABORATORIES;BRUNCKO, MILAN;DING, HONG;DOHERTY, GEORGE, A.;ELMORE, STEVEN, W.;HASVOLD, LISA;HEXAMER, LAURA;KUNZER, AARON, R.;MANTEI, ROBERT, A.;MCCLELLAN, WILLIAM, J.;PARK, CHANG, H.;PARK, CHEOL-MIN;PETROS, ANDREW, M.;SONG, XIAOHONG;SOUERS, ANDREW, J.;SULLIVAN, GERARD, M.;TAO, ZHI-FU;WANG, GARY, T.;WANG, LE;WANG, XILU;WENDT, MICHAEL, D. 发明人 BRUNCKO, MILAN;DING, HONG;DOHERTY, GEORGE, A.;ELMORE, STEVEN, W.;HASVOLD, LISA;HEXAMER, LAURA;KUNZER, AARON, R.;MANTEI, ROBERT, A.;MCCLELLAN, WILLIAM, J.;PARK, CHANG, H.;PARK, CHEOL-MIN;PETROS, ANDREW, M.;SONG, XIAOHONG;SOUERS, ANDREW, J.;SULLIVAN, GERARD, M.;TAO, ZHI-FU;WANG, GARY, T.;WANG, LE;WANG, XILU;WENDT, MICHAEL, D.
分类号 C07D405/12;A61K31/404;A61P35/00;C07D209/32;C07D211/96;C07D213/64;C07D215/20;C07D217/16;C07D235/26;C07D249/04;C07D295/125;C07D295/14;C07D309/14;C07D401/12 主分类号 C07D405/12
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