METHODS AND COMPOSITIONS FOR LIPOSOMAL FORMULATION OF ANTIGENS AND USES THEREOF
摘要
The present invention relates to liposomal vaccine compositions, methods for the manufacture thereof, and methods for the use thereof to stimulate an immune response in an animal. These compositions comprise dimyristoylphosphatidylcholine ("DMPC"); either dimyristoylphosphatidylglycerol ("DMPG") or dimyristoyltrimethylammonium propane ("DMTAP") or both DMPC and DMTAP; and at least one sterol derivative providing a covalent anchor for one or more immunogenic polypeptide(s) or carbohydrate(s).
申请公布号
CA2754896(A1)
申请公布日期
2010.09.16
申请号
CA20102754896
申请日期
2010.03.09
申请人
MOLECULAR EXPRESS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人
FUJII, GARY;SZOKA, FRANCIS C., JR.;WATSON, DOUGLAS S.