发明名称 |
TRANSGENIC ANIMALS FOR ASSESSING DRUG METABOLISM AND TOXICITY |
摘要 |
The present invention relates to transgenic non-human animals, tissues or cells derived therefrom and methods of producing them. The transgenic non-human animals or tissues or cells derived therefrom provide a system capable of expressing human proteins responsible for drug metabolism in place of the homologous endogenous non-human animal proteins and for the controlled expression of human genes introduced into the animal so that the expression of the human genes is regulated in a manner more closely analogous to that seen in vivo in humans.
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申请公布号 |
US2010235928(A1) |
申请公布日期 |
2010.09.16 |
申请号 |
US20100787816 |
申请日期 |
2010.05.26 |
申请人 |
ITI LIFE SCIENCES |
发明人 |
WOLF CHARLES ROLAND;SCHEER NICO;FAUST NICOLE |
分类号 |
A01K67/00;C12N5/10;C12N15/85 |
主分类号 |
A01K67/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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