METHODS FOR THE DETERMINATION OF A COPY NUMBER OF A GENOMIC SEQUENCE IN A BIOLOGICAL SAMPLE
摘要
<p>Methods for the determination of a copy number of a target genomic sequence; either a target gene or genomic sequence of interest, in a biological sample are described. Various methods utilize a model drawn from a probability density function (PDF) for the assignment of a copy number of a target genomic sequence in a biological sample. Additionally, the methods provide for the determination of a confidence value for a copy number assigned to a sample based on attributes of the sample data. Accordingly, the various methods for the determination of a copy number provide the end user with significant information for the evaluation of a copy number of a target genomic sequence; either a gene or genomic sequence of interest.</p>
申请公布号
WO2010104893(A2)
申请公布日期
2010.09.16
申请号
WO2010US26726
申请日期
2010.03.09
申请人
LIFE TECHNOLOGIES CORPORATION;LEONG, HARRISON M.;BARBACIORU, CATALIN;JANAWAY, GORDON A.
发明人
LEONG, HARRISON M.;BARBACIORU, CATALIN;JANAWAY, GORDON A.