发明名称 |
SUBSTITUTED HETEROCYCLES AND THEIR USE AS ALLOSTERIC MODULATORS OF NICOTINIC AND GABAA RECEPTORS |
摘要 |
The present invention is related to heterocycles represented by a compound of Formula (I) that are novel allosteric modulators of a7 nAChRs and/or GABAA receptors. The invention also discloses the treatment of disorders that are responsive to enhancement of acetylcholine action on a7 nAChRs and negative allosteric modulation of GABAA receptors in a mammal by administering an effective amount of a compound of Formula (I).
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申请公布号 |
CA2754180(A1) |
申请公布日期 |
2010.09.16 |
申请号 |
CA20102754180 |
申请日期 |
2010.03.09 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
JOHNSTONE, TIMOTHY B.C.;HOGENKAMP, DERK J.;GEE, KELVIN W. |
分类号 |
C07D487/04;A61P25/00;C07D403/02;C07D403/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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