| 摘要 |
The invention provides a method for treating, preventing or ameliorating a hyperproliferative disease and/or disorder such as cancer (e.g. leukemia) in a mammal comprising administering a therapeutically effective amount of one or more compounds selected from the group consisting of compounds of Formula (I), quinolones and fluoroquinolones; or a pharmaceutically acceptable salt thereof to said mammal: wherein R1 comprises a structural moiety represented by X—C(O)—CH—NH (X=O or S). The invention also provides a combination therapy method using such compounds in combination with other cancer fighting chemicals. The invention exhibits merits such as none or minimal side effect associated with chemotherapy.
|
