发明名称 |
A POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCE AND METHODS THEREOF |
摘要 |
<p>The present disclosure relates to a field of recombinant DNA therapeutics. It involves the bio-informatics design, synthesis of artificial gene for human insulin precursor including leader peptide coding sequence, cloning in an expression vector and expression in an organism, preferably Pichia pastoris. The present disclosure also relates to methods of downstream processing for obtaining protein precursor molecules and subsequent conversion of precursor molecules to functional proteins.</p> |
申请公布号 |
CA2755300(A1) |
申请公布日期 |
2010.09.16 |
申请号 |
CA20102755300 |
申请日期 |
2010.03.12 |
申请人 |
BIGTEC PRIVATE LIMITED |
发明人 |
MANOJ, MULAKKAPURATH NARAYANAN;VASAMSETTY, VENKATA RAMACHANDRA RAO;BALIGA, MADHURI;KUMAR, KIRUBAKARAN NAVEEN;NAIR, CHANDRASEKHAR BHASKARAN;SUBBARAO, PILLARISETTI VENKATA |
分类号 |
C12N15/17;C07K1/107;C07K1/18;C07K1/20;C07K1/34;C07K1/36;C07K14/62;C12N15/81 |
主分类号 |
C12N15/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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