BIOBURDEN-REDUCING ANTIBIOTIC COMPOSITION AND METHOD OF USE
摘要
An antibiotic composition is provided for use in decontaminating biological tissue. For example, graft tissues for transplantation or preparation For terminal sterilization. The antibiotic composition is a physiological solution includes a antibiotic, such as nisin. The antibiotic solution is effective to substantially inhibit bacterial growth of at least one type of gram-positive bacteria while substantially maintaining the physiological characteristics of the tissue. The method may include contacting the tissue with the antimicrobial composition at a temperature and for a period of time effective to substantially inhibit bacterial growth of the at least one type of gram-positive bacteria while substantially maintaining the physiological characteristics of the tissue.
申请公布号
WO2010105021(A2)
申请公布日期
2010.09.16
申请号
WO2010US26923
申请日期
2010.03.11
申请人
CRYOLIFE, INC.;WALSH, STEVEN;HAMBY, JOSEPH;CHINICH, CHAD