IMPROVED METHOD FOR PRODUCING HYALURONIC ACID

摘要

PROBLEM TO BE SOLVED: To provide a method for producing hyaluronic acid efficiently.

SOLUTION: The method for producing hyaluronic acid comprises: constructing an expression vector which includes a DNA encoding a protein having the hyaluronic acid synthesis activity under the control of a promoter and a transcription termination region functional in plant and a DNA encoding a protein having the glutamine-fructose-6-phosphate amidotransferase activity under the control of a promoter and a transcription termination region functional in plant and/or a DNA encoding a protein having the UDP-glucose dehydrogenase activity under the control of a promoter and a transcription termination region functional in plant; obtaining a transformant by transforming plant cells or plants using the vector; and culturing the transformant; and the process of separating hyaluronic acid produced by the transformant.

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