发明名称 |
Heterocycle Substituted Ketone Derivatives as Histone Deacetylase (HDAC) Inhibitors |
摘要 |
The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts and tautomers thereof. Compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. They are also useful for treating neurodegenerative diseases, mental retardation, schizophrenia, inflammatory diseases, restenosis, immune disorders, diabetes, cardiovascular disorders and asthma.
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申请公布号 |
US2010234374(A1) |
申请公布日期 |
2010.09.16 |
申请号 |
US20060086812 |
申请日期 |
2006.12.21 |
申请人 |
JONES PHILIP;ONTORIA ONTORIA JESUS MARIA;SCARPELLI RITA;INGENITO RAFFAELE;SCHULTZ-FADEMRECHT CARSTEN |
发明人 |
JONES PHILIP;ONTORIA ONTORIA JESUS MARIA;SCARPELLI RITA;INGENITO RAFFAELE;SCHULTZ-FADEMRECHT CARSTEN |
分类号 |
A61K31/4164;A61K31/4172;A61K31/4196;A61K31/427;A61K31/4439;A61K31/454;A61K31/4709;A61K31/496;A61K31/5377;A61P3/10;A61P9/00;A61P9/10;A61P11/06;A61P25/00;A61P25/18;A61P25/28;A61P29/00;A61P35/00;A61P37/02;C07D233/64;C07D401/06;C07D401/12;C07D403/06;C07D403/12;C07D413/12;C07D417/12 |
主分类号 |
A61K31/4164 |
代理机构 |
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地址 |
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