发明名称 Fc Variants with altered binding to FcRn
摘要 The present application relates to a variant Fc region comprising at least one modification relative to a wild-type human Fc region, where the modification selected from the group consisting of 434S, 252Y/428L, 252Y/434S, and 428L/434S, and the numbering is according to the EU index.
申请公布号 US2010234574(A1) 申请公布日期 2010.09.16
申请号 US20100697952 申请日期 2010.02.01
申请人 XENCOR, INC. 发明人 CHAMBERLAIN AARON KEITH;DAHIYAT BASSIL I.;DESJARLAIS JOHN R.;KARKI SHER BAHADUR;LAZAR GREGORY ALAN
分类号 C07K16/00 主分类号 C07K16/00
代理机构 代理人
主权项
地址