发明名称 |
GRUPPE NEUER ENANTIOSELEKTIVER MIKROBIELLER NITRILHYDRATASEN MIT BREITER SUBSTRATSPEZIFITÄT |
摘要 |
The present invention provides a polynucleotide or a pair of polynucleotides encoding an enzyme having nitrile hydratase (NHase) [E.C. 4.2.1.84] activity. Furthermore, a vector and a host comprising the disclosed polynucleotide or pair of polynucleotides and methods for the production of the same are provided. Moreover, the invention relates to a pair of polypeptides or a fusion protein having NHase activity, an antibody specifically binding to the pair of polypeptides or fusion protein, a primer or probe, which specifically hybridizes under stringent conditions to the disclosed polynucleotide or either one of the pair of polynucleotides, a composition comprising the polynucleotide or pair of polynucleotides, the pair of polypeptides or fusion protein, the antibody and/or one or more primers or probes of the invention and a method for the production of amides comprising the enantioselective conversion of nitriles. |
申请公布号 |
AT480617(T) |
申请公布日期 |
2010.09.15 |
申请号 |
AT20070724055T |
申请日期 |
2007.04.05 |
申请人 |
B.R.A.I.N. AG |
发明人 |
ECK, JUERGEN;LIEBETON, KLAUS;FISCHER, LUTZ;LUTZ-WAHL, SABINE;HENSEL, MARTINA;EWERT, CHRISTIAN;WAELZ, MARCUS |
分类号 |
C12N9/14;C07K14/195;C12N1/20;C12N9/78;C12P13/02;C12P41/00 |
主分类号 |
C12N9/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|