发明名称 PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY
摘要 <p>The present invention is a compound having the general formula (I), (II), or (III) or a pharmacologically acceptable salt, solvate, or hydrate thereof, and a pharmaceutical composition containing such a compound, or its pharmacologically acceptable ester, or other pharmacologically acceptable derivative thereof as an active ingredient. The compound has an excellent ACAT 2-inihibiting activity by a mechanism different from that of a statin drug and is useful as a therapeutic or prophylactic agent for obesity, adiposis, hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, and arteriosclerosis, as well as obesity-derived hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, arteriosclerosis, and hypertension.</p>
申请公布号 EP2228376(A1) 申请公布日期 2010.09.15
申请号 EP20080864334 申请日期 2008.12.17
申请人 THE KITASATO INSTITUTE 发明人 TOMODA, HIROSHI;NAGAMITSU, TOHRU;OMURA, SATOSHI
分类号 C07D493/04;A61K31/4433;A61K31/695;A61P9/10;A61P43/00;C07D493/14;C07F7/18 主分类号 C07D493/04
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