发明名称 |
Modulation of granulosa cell apoptosis |
摘要 |
The present invention relates to a culture medium for an oocyte and/or an embryo, the medium including either or both of (i) GDF-9 or a variant thereof; and (ii) an agent that increases the activity of a GDF-9 dependent signalling pathway in one or more of an oocyte, a cumulus cell associated with an oocyte, and an embryo; and to methods using such culture medium. |
申请公布号 |
EP2228070(A2) |
申请公布日期 |
2010.09.15 |
申请号 |
EP20100004342 |
申请日期 |
2006.07.18 |
申请人 |
ADELAIDE RESEARCH & INNOVATION PTY LTD |
发明人 |
GILCHRIST, ROBERT BRUCE;THOMPSON, JEREMY;HUSSEIN, TAMER |
分类号 |
A61K38/18;C12N5/073;C12N5/075 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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