| 摘要 |
In the present invention, there is disclosed a device for the transdermal administration of nicotine comprising a backing layer, a drug reservoir layer containing nicotine carried by said backing layer, and means for maintaining the device in nicotine transmitting relationship with the skin, wherein the device is sufficiently transparent to permit the skin of the subject to which it is applied to be visible through said device wherein said backing is formed from a material selected from the group consisting of PET/EVA laminates, HDPE/EAA/nylon/EAA multilaminate and a film comprising a graft copolymer formed from about 73 to 77 percent acrylonitrile and from about 23 to 27 percent methyl acrylate copolymerized in the presence of about 8 to 10 parts by weight of butadiene/acrylonitrile copolymers containing approximately 70 percent by weight of polymer units derived from butadiene, and the device has an Opacity Index of less than 48.6 percent. |
