| 发明名称 |
N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders |
| 摘要 |
The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.
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| 申请公布号 |
US7795440(B2) |
申请公布日期 |
2010.09.14 |
| 申请号 |
US20070657912 |
申请日期 |
2007.01.25 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
HO CHIH YUNG;BRUNMARK BENGT ANDERS;EMANUEL STUART;GALEMMO, JR. ROBERT A.;JOHNSON DANA L.;LUDOVICI DONALD W.;MAHAROOF UMAR;MEI JAY M.;SECHLER JAN L.;STROBEL ERIC D.;TUMAN ROBERT W.;YEN HWA KWO |
| 分类号 |
A61K31/416;A61K31/4439;A61P35/04;C07D231/54;C07D231/56;C07D233/54;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D413/12;C07D491/04;C07D495/04;C07D498/04;C07F9/6503 |
主分类号 |
A61K31/416 |
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