发明名称 |
SYNTHESIS OF AMINO ACID, N-CARBOXYANHYDRIDES |
摘要 |
A process for producing N-carboxyanhydrides is disclosed. The process produces N-carboxyanhydrides as a product and HCl as a by-product. The HCl by-product is purged from the reaction mixture by passing a purge gas through the reaction mixture as a carbonylation reagent is reacting with an amino acid or a salt thereof. The N-carboxyanhydrides produced by this process have a relatively lower chloride impurity content, relatively higher yields can be achieved, and the N-carboxyanhydrides can be produced on a larger scale.
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申请公布号 |
CA2584311(C) |
申请公布日期 |
2010.09.14 |
申请号 |
CA20052584311 |
申请日期 |
2005.10.26 |
申请人 |
SIGMA-ALDRICH CO. |
发明人 |
CARUBIA, JOHN MICHAEL;WEAVER, THOMAS MARK;PONNUSAMY, ETTIGOUNDER |
分类号 |
C07D263/04 |
主分类号 |
C07D263/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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