| 摘要 |
Disclosed are compounds: (see formula I) (see formula II) (see formula III) (see formula IV) (see formula V) (see formula VI) and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. The compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho--kinase, e.g., coronary heart disease.
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