BIODEGRADABLE POROUS HOLLOW PARTICLE, AND PRODUCTION METHOD AND APPLICATION THEREOF

摘要

Disclosed is a method where pore diameter and other attributes can be easily controlled, and which can produce porous particles with a novel form having a hollow section. Namely, disclosed is a production method for porous particles formed from a diblock copolymer which includes a step where water, an organic solvent, and the abovementioned diblock copolymer comprising a site derived from a particular aliphatic polyester resin (polylactic acid, etc.) and a site derived from a hydrophilic macromolecule (polyethylene glycol, etc.) are emulsified or admixed. Porous particles having a hollow section are obtained by making the quantity of the abovementioned water less than or equal to the quantity to saturate the abovementioned organic solvent. The pore diameter of the porous particles can be made relatively larger by making the length of the hydrophilic macromolecule site in the abovementioned diblock copolymer relatively longer (increasing the hydrophilic-lipophilic balance value). Furthermore, the abovementioned diblock copolymer may also include a mixture of at least two types (e.g. an oil-soluble diblock copolymer and a water-soluble diblock copolymer).