| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, oncology, and can be used for treating rectal cancer. That is ensured by daily 5-fluorouracil chemotherapy for 5 days combined with the following introduction of a platinum preparation. It is followed with gamma therapy according to the dynamic dose fractionation with the amplified fractions of 4 Gy for the first 3 days. Further, said ray therapy is ensured by small fractions in the superfractionation mode, twice a day, every 4-5 hours, of 1.25 Gy to total basic dose of 47.0 Gy. In addition, every night at bedtime, Derinat gel is introduced in microenemas of 5-10 ml for the first 5 days of treatment, of 10-20 ml in amplified fraction radiation, of 30-35 ml in small fraction radiation, of 25-30 ml after the termination of the radiation course for 2 weeks. ^ EFFECT: method provides increasing TBD to 47,0 Gy that is an equivalent of 50 Gy of conventional radiation dose fractionation, as normal tissues allow delivering the specified dose without the evident ray-induced reactions. ^ 2 ex |
