发明名称 |
USE OF 5AHQ AND BORTEZOMIB FOR THE TREATMENT OF HEMATOLOGICAL DISEASES |
摘要 |
The disclosure provides methods and compositions for treating hematological malignancies. In particular, the disclosure provides methods and compositions for treating leukemia, lymphoma and multiple myeloma using bortezomit and 5AHQ (5-ammo-8-hydroxyqumolme) and related compounds that bind non-competitively to an alpha unit of 2OS proteasome and inhibit proteasome activity Kits and commercial packages are also disclosed |
申请公布号 |
WO2010099601(A1) |
申请公布日期 |
2010.09.10 |
申请号 |
WO2010CA00282 |
申请日期 |
2010.03.02 |
申请人 |
UNIVERSITY HEALTH NETWORK;SCHIMMER, AARON, D. |
发明人 |
SCHIMMER, AARON, D. |
分类号 |
A61K31/69;A61K31/47;A61P35/00;A61P35/02 |
主分类号 |
A61K31/69 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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