SIGMA 1 RECEPTOR INHIBITION AS A NOVEL THERAPEUTICAL APPROACH AGAINST HEPATITIS C VIRUS INFECTION

摘要

A method for treating or ameliorating the symptoms of a Hepatitis C virus infection comprising administering a Sigma 1 receptor binding compound or an interfering RNA is provided. Methods for identifying a compound that inhibits a Hepatitis C virus infection are also provided. The Sigma 1 receptor binding compound or interfering RNA is believed to act by reducing the susceptibility of uninfected human cells to infection by Hepatitis C virus, inhibiting viral spread in a cellular population.