发明名称 COMBINATION CONTAINING N-(3-METHOXY-5-METHYLPYRAZINE-2-YL)-2-(4-[1,3,4-OXADIAZOL-2-YL]PHENYL)PURIDINE-3-SULPHONAMIDE AND LHRH-ANALOGUE AND/OR BIPHOSPHONATE
摘要 <p>FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to medical products and concerns a combination for prostate cancer treatment containing effective amounts of N-(3-methoxy-5-methylpyrazine-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide or its pharmaceutically acceptable salt and pamidronate. There is also disclosed a method of prostate cancer treatment and application of the combination for preparing a medicinal agent used in prostate cancer treatment. ^ EFFECT: combination under the invention exhibits synergetic effect with respect to inhibiting metastases to bone and soft tissues in prostate cancer treatment. ^ 4 cl</p>
申请公布号 RU2398588(C2) 申请公布日期 2010.09.10
申请号 RU20060110736 申请日期 2004.09.02
申请人 ASTRAZENEKA AB 发明人 GALLAER NIL;KERUEHN DZHON OUEHN
分类号 A61K31/497;A61K31/663;A61K31/675;A61K38/09;A61K45/06;A61P35/00 主分类号 A61K31/497
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