| 摘要 |
FIELD: medicine. ^ SUBSTANCE: there are produced multipurpose and polyvalent inhibitors prepared of fused proteins containing polypeptide which identifies and blocks a functional site of molecule involved in angiogenesis, and polypeptide containing oligomerisation domain and a functional site modulating or inhibiting angiogenesis and separated by a proteinase sensitive site. ^ EFFECT: inhibitors are suitable for treatment and prevention of the pathologies caused by angiogenesis, eg a malignant tumour, rheumatoid arthritis or psoriasis. ^ 25 cl, 6 dwg, 1 tbl, 1 ex |
