发明名称 THERAPEUTIC USES OF CHEMOKINE VARIANTS
摘要 The invention relates to the use of a polypeptide comprising SEQ ID NO : 2 (CCL2-8PA) or SEQ ID NO : 4 (CCL2*-8PA) as medicament for the treatment of autoimmune, inflammatory or infectious diseases; fusion polypeptide amino acid sequence of SEQ ID NO : 2 fused to the constant region of a human immunoglobulin heavy chain of SEQ ID NO : 5, a method for producing the fusion polypeptide. Polypeptides disclosed can be used as active ingredient in pharmaceutical compositions for the treatment of inflammatory, autoimmune, or infectious diseases.
申请公布号 UA91820(C2) 申请公布日期 2010.09.10
申请号 UA20060004131 申请日期 2004.10.18
申请人 MERCK SERONO S.A. 发明人 PROUDFOOT AMANDA;SHAW JEFFREY;JOHNSON ZOE
分类号 A61K38/19;C07K14/52;G01N33/68 主分类号 A61K38/19
代理机构 代理人
主权项
地址