发明名称 |
Methods for the synthesis of arrays of DNA probes |
摘要 |
The synthesis of arrays of DNA probes sequences, polypeptides, and the like is carried out using a patterning process on an active surface of a substrate. An image is projected onto the active surface of the substrate utilizing reflective projection optics. The projection optics project a light image onto the active surface of the substrate to deprotect linker molecules thereon. A first level of bases may then be applied to the substrate, followed by development steps, and subsequent exposure of the substrate utilizing a different light image, with further repeats until the elements of a two dimensional array on the substrate surface have an appropriate base bound thereto.
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申请公布号 |
US2010227780(A1) |
申请公布日期 |
2010.09.09 |
申请号 |
US20060524082 |
申请日期 |
2006.09.20 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
CERRINA FRANCESCO;SUSSMAN MICHAEL R.;BLATTNER FREDERICK R.;SINGH-GASSON SANGEET;GREEN ROLAND |
分类号 |
C40B50/18;G01N33/53;B01J19/00;C07B61/00;C07H21/00;C08K3/00;C12M1/34;C12Q1/68;C40B40/06;C40B60/14;G01N21/05;G01N21/17;G01N37/00;G02B26/08;G03F7/20 |
主分类号 |
C40B50/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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