发明名称 |
AFFINITY STRUCTURES FOR THE SPECIFIC BINDING OF SUBSTANCES BY MEANS OF NON-COVALENT INTERACTION SHAPES |
摘要 |
A method for producing affinity binders having affinitive or highly affinitive binding structures for non-covalent interaction types includes a) contacting a target substance with at least one ligand which is capable of non-covalently binding to the target substance for a sufficient time that the at least one ligand can specifically attach to target regions of the target substance and form a ligand-target substance complex; b) embedding the complex in a structure-providing component and fixing by binding the ligand(s) of the complex to the structure-providing component; and c) removing the target substance such that a structure with a defined spatial arrangement of the ligand(s) is formed which has capacity to specifically bind the respective target substance again. |
申请公布号 |
EP2225560(A1) |
申请公布日期 |
2010.09.08 |
申请号 |
EP20080853543 |
申请日期 |
2008.11.25 |
申请人 |
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. |
发明人 |
ANDRESEN, HEIKO;BIER, FRANK;KATTERLE, MARTIN |
分类号 |
G01N33/53;C08G63/91;G01N33/531 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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