| 发明名称 |
14-3-3 ANTAGONISTS FOR THE PREVENTION AND TREATMENT OF ARTHRITIS |
| 摘要 |
The invention provides anti-14-3-3 eta antibodies that specifically bind to the human 14-3-3 eta protein isoform in its natural configuration while exhibiting selectivity over human 14-3-3 alpha, beta, delta, epsilon, gamma, tau, and zeta protein isoforms. Methods, kits and pharmaceutical compositions comprising said specific anti-14-3-3 eta antibodies are further provided for the diagnosis and treatment of arthritis. |
| 申请公布号 |
EP2224955(A1) |
申请公布日期 |
2010.09.08 |
| 申请号 |
EP20080853323 |
申请日期 |
2008.11.26 |
| 申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
MAROTTA, ANTHONY;GHAHARY, AZIZ;MAKSYMOWYCH, WALTER, WOLODYMYR, PETER;KILANI, RUHANGIZ |
| 分类号 |
C07K16/18;A61K39/395;A61P19/02;C07K16/00;G01N33/53;G01N33/543 |
主分类号 |
C07K16/18 |
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