| 发明名称 |
Preparation of human, humanized or chimaeric antibodies or polypeptides having different binding profiles to Fcgamma receptors |
| 摘要 |
The present invention relates to a method for the production and the selection of human or chimæric or humanized antibodies or molecules that comprise the Fc region of human IgG, capable of modulating the activity of one or several particular Fc receptors, such as the triggering of inhibitory functions through the human type IIB receptors of IgG (FcgammaRIIB/CD32).
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| 申请公布号 |
US7790399(B2) |
申请公布日期 |
2010.09.07 |
| 申请号 |
US20040551819 |
申请日期 |
2004.04.05 |
| 申请人 |
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLGIES (LFB);INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
BOUREL DOMINIQUE;DE ROMEUF CHRISTOPHE;SIBERIL SOPHIE;FRIDMAN WOLF HERMAN;TEILLAUD JEAN-LUC;BIHOREAU NICOLAS;NONY EMMANUEL |
| 分类号 |
G01N33/53;C07K16/00;C07K16/28;C07K16/34 |
主分类号 |
G01N33/53 |
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