发明名称 |
THE 74 KILODALTON OUTER MEMBRANE PROTEIN FROM MORAXELLA CATARRHALIS |
摘要 |
A protein from the M. catarrhalis designated the 74 kD protein is isolated and purified. The 74 kD protein has an amino-terminal amino acid sequence which is conserved among various strains of M. catarrhalis. The protein has a molecular weight of approximately 74,9 kD as measured on a 10 % SDS-PAGE gel, while its molecular weight as measured by mass spectrometry is approximately 74 kD. The 74 kD protein is used to prepare a vaccine composition which elicits a protective immune response in a mammalian host to protect the host again disease caused by M. catarrhalis.
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申请公布号 |
CA2277999(C) |
申请公布日期 |
2010.09.07 |
申请号 |
CA19982277999 |
申请日期 |
1998.01.29 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
CHEN, DEXIANG;VANDERMEID, KARL R.;MCMICHAEL, JOHN C.;BARNIAK, VICKI L. |
分类号 |
C07K14/22;A61K38/00;A61K39/00;A61K39/095;C07K14/21 |
主分类号 |
C07K14/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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