发明名称 |
Angiogenesis inhibiting molecules and their use in the treatment and diagnosis of cancer |
摘要 |
The present invention relates to angiogenesis inhibiting molecules that are the monoclonal antibody H33 or fragments or derivatives thereof, to their use in the treatment of cancer, in particular the treatment of solid tumors and to therapeutic and diagnostic compositions comprising them. The invention relates in particular to humanized derivatives of H33 of human monoclonal antibodies having the specificity of H33.
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申请公布号 |
US7790863(B2) |
申请公布日期 |
2010.09.07 |
申请号 |
US20040579105 |
申请日期 |
2004.11.19 |
申请人 |
MERCK SERONO S.A. |
发明人 |
IMHOF BEAT A.;AURRAND-LIONS MICHEL |
分类号 |
C07K16/28;A61K38/17;A61K39/395;C07K14/705;C12N5/20;C12P21/08;G01N33/53;G01N33/566;G01N33/574;G01N33/577 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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