发明名称 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF
摘要 The compound represented by formulae (I) and (II), the salt thereof, the N-oxide thereof or the solvate thereof, or the prodrug thereof and the pharmaceutical composition comprising thereof have a CXCR4-regulating effect, and they are effective in treatment and prevention of various inflammatory disease, various allergic disease, acquired immunodeficiency syndrome infection with human immunodeficiency virus, or agents for regeneration therapy. (wherein ring A represents a nitrogen-containing heterocyclic group which may have a substituent(s); ring B represents a homocyclic group which may have a substituent(s) or a heterocyclic group which may have a substituent(s); and Y represents a hydrocarbon group which may have a substituent(s), a heterocyclic group which may have a substituent(s), an amino group which may be protected, a hydroxyl group which may be protected or a mercapto group which may be protected; T represents ring A or an amino group which may be protected.)
申请公布号 US2010221259(A1) 申请公布日期 2010.09.02
申请号 US20100776989 申请日期 2010.05.10
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 HABASHITA HIROMU;KOKUBO MASAYA;SHIBAYAMA SHIRO;TADA HIDEAKI;TANIHIRO TATSUYA
分类号 A61K39/42;A61K31/506;A61K31/517;A61K31/5377;A61K31/541;A61K31/55;A61K31/551;A61K31/69;A61K31/7064;A61K31/7072;A61K31/708;A61K39/00;A61P3/00;A61P9/00;A61P25/00;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;A61P37/02;A61P37/08;A61P43/00;C07D221/22;C07D239/48;C07D239/95;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D403/14;C07D405/12;C07D405/14;C07D409/14;C07D413/04;C07D413/14;C07D417/04;C07D493/04;C07D493/10;C07F5/02;C07H15/26 主分类号 A61K39/42
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