| 发明名称 |
INHIBITORS OF MRE11, RAD50 AND/OR NBS1 |
| 摘要 |
The invention provides, inter alia, compositions comprising an inhibitor of MRE11, RAD50 and/or NBSl and methods of using such inhibitor for modulating the cellular response to DNA damage, arresting the cell cycle, and/or treatment of cancer. The inhibitor is, e.g., a compound of formula I:
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| 申请公布号 |
WO2010075372(A9) |
申请公布日期 |
2010.09.02 |
| 申请号 |
WO2009US69171 |
申请日期 |
2009.12.22 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;GAUTIER, JEAN;KOPELOVICH, LEVY |
发明人 |
GAUTIER, JEAN;KOPELOVICH, LEVY |
| 分类号 |
A61K31/41 |
主分类号 |
A61K31/41 |
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