SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE

摘要

Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of theδopioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and otherδopioid receptor-mediated conditions.