发明名称 COMPOSITION INHIBITING PROLIFERATION OF CANCER CELL
摘要 PROBLEM TO BE SOLVED: To provide compositions and methods relating to integrin-mediated cancer cell proliferation. SOLUTION: There are provided compositions and methods for reducing the proliferation of cancer cells through targeted interactions with integrins. In detail, a method for decreasing proliferation of cancer cells, including a step of inhibiting ligand bonding to an integrin receptor on the cancer cells, wherein the integrin receptor includes integrin. The cancer cell is selected from the group consisting of Melanoma cell, Adenophyma cell, Lymphoma cell, Myeloma cell, Carcinoma cell, Plasmacytoma cell, Sarcoma cell, Glioma cell, Thymoma cell, Leukemic cell, Carcinoma cutaneum cell, Retina cancer cell, Breast cancer cell, Prostatic cancer cell, Colon cancer cell, Esophageal cancer cell, Stomach cancer cell, Pancreas cancer cell, Brain tumor cell, Lung cancer cell, Ovarian cancer cell, Cervix cancer cell, Liver cancer cell, gastrointestinal cancer cell, and head and neck cancer cell. COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2010189445(A) 申请公布日期 2010.09.02
申请号 JP20100131521 申请日期 2010.06.08
申请人 UNIV OF ROCHESTER 发明人 LAND HARTMUT;DELEU LAURENT
分类号 A61K45/00;A61K47/48;A61K31/7084;A61K31/7088;A61K35/76;A61K38/00;A61K38/17;A61K45/06;A61K48/00;A61P35/00;A61P35/02;A61P43/00;C07K14/705;C12N15/113 主分类号 A61K45/00
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