<p>The present invention is directed to pharmaceutical compositions comprising: (a) bendamustine, (b) a charged cyclopolysaccharide, and (c) a stabilizing agent having a charge opposite to that of the cyclopolysaccharide. Such composition provides unexpectedly desirable stability in reactive environments such as plasma, coupled with unexpectedly desirable anticancer activity. Such compositions are suitable for injection or infusion into patients in need for treatment with bendamustine.</p>
申请公布号
WO2010097700(A1)
申请公布日期
2010.09.02
申请号
WO2010IB00502
申请日期
2010.02.24
申请人
SUPRATEK PHARMA, INC.;POPEK, TOMASZ;PATEL, KISHORE;ALAKHOV, VALERY;PIETRZYNSKI, GRZEGORZ
发明人
POPEK, TOMASZ;PATEL, KISHORE;ALAKHOV, VALERY;PIETRZYNSKI, GRZEGORZ